SOUTH Australian Premier Jay Weatherill has warned that up to 16,000 jobs could be lost if Holden were to close in Elizabeth.

Mr Weatherill has tabled a report in state parliament that he says shows the importance of supporting the car maker's operations.

The premier has repeatedly insisted the state government will invest to keep General Motors-Holden in South Australia for the next decade and beyond.

The car maker, which employs 2000 people at Elizabeth, in northern Adelaide, has been in negotiations with state and federal governments about assistance for its operations in Australia beyond 2015.

Mr Weatherill told parliament yesterday that if the Elizabeth plant closed it would cause the loss of between 6000 and 16,000 jobs around the state.

It also would reduce the value of economic activity by between $0.5 billion and $1.5 billion, he said.