TV personality Bert Newton will undergo quadruple bypass heart surgery in Melbourne.

Mr Newton is at Melbourne's Epworth hospital, where he will undergo the five-and-a-half hour surgery at 6am tomorrow, the Nine Network said.

"I couldn't say I'm scared (but) apprehensive," he told Nine on Friday.

Mr Newton's family are by his bedside in a private hospital room.

"Things like this, it does depend on attitude," he said.

"I think I have a good attitude and a very positive attitude, which is important.

"I got a family that I want to be with for a long time."