UPDATE: A PASSENGER train and a truck have collided at Lake Charm in Victoria's north west this afternoon.

Emergency services personnel breathed a collective sigh of relief after discovering no one had been seriously injured in the collision.

It was a far cry from the scene that greeted them when they responded to the infamous 2007 train and truck crash less than 10km away at the Murray Valley Highway level crossing near Kerang which killed 11 people.

This time the train and its three carriages stayed on the track, stopping after several hundred metres.

Paramedics checked everyone, including the four crew, before State Emergency Service and CFA volunteers helped the 40 passengers disembark safely.

V/line regional manager James Edmiston said the 12.50pm train from Swan Hill was on its way to Melbourne when it struck the truck about 1.30pm.

Mr Edmiston said coaches were called in to take the passengers to Bendigo and Melbourne.

The train driver, aged 49, of Cockatoo, said had been involved in crashes before, but it was the first time he had hit a truck in 32 years of working with V/line.

''I'm absolutely relieved that no one was injured,'' he said.

At the end of the day, the truck driver's OK, the passengers and crew are OK. Nothing else matters.''

The train driver said it was fortunate that the truck was fully laden, otherwise it might have spun back into the train instead of being pushed out of the way.

The truck driver, a 40-year-old farmer from Berrigan, in NSW, said he had been on his way home with a load of gypsum when the train struck the back of his trailer as he was passing over the raised railway crossing on McCann Road.

The force of the impact ripped off the trailer's tailgate, tore away the back set of wheels and mangled the railway crossing and give way signs

The driver, who declined to give his name, said the $75,000 trailer was less than 12 months old.

It was his second trip this week to pick up gypsum to be spread onto canola crops, he said.

An assessment of the railway line was completed this afternoon and it was declared safe.

The train sustained a shattered windscreen and damage to the front of the engine, but was thought to be structurally sound.

It was expected to be driven slowly to Melbourne for repairs.

Train services will operate as normal from tonight's 6.20pm train from Southern Cross to Swan Hill.